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當(dāng)前位置:首頁技術(shù)文章WASP抗原,濕疹血小板減少伴免疫缺陷綜合征相關(guān)蛋白抗原

WASP抗原,濕疹血小板減少伴免疫缺陷綜合征相關(guān)蛋白抗原

更新時(shí)間:2024-11-14點(diǎn)擊次數(shù):249

Recombinant human WASP protein   

Eczema thrombocytopenia; IMD2; SCNX; THC; THC1; Thrombocytopenia 1 (X linked); U42471; Was; WASp; WASP_HUMAN; Wiskott Aldrich syndrome (eczema thrombocytopenia); Wiskott Aldrich syndrome; Wiskott Aldrich syndrome protein; Wiskott-Aldrich syndrome protein.   

濃度:1mg/ ml

來源:Recombinant Human

純度:95% SDS-PAGE

表達(dá)系統(tǒng):Escherichia coli

標(biāo)簽:His tag   

蛋白長度:Full length protein

內(nèi)毒素水平:<1.000 Eu/µg

純化方法:HPLC

應(yīng)用:SDS-PAGE,Western blot,ELISA

Biological activity,immunology research

保存:-20

保質(zhì)期:1

The Wiskott-Aldrich syndrome (WAS) is a disorder that results from a monogenic defect that has been mapped to the short arm of the X chromosome. WAS is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative disease. The gene that is mutated in the syndrome encodes a proline-rich protein of unknown function designated WAS protein (WASP). A clue to WASP function came from the observation that T cells from affected males had an irregular cellular morphology and a disarrayed cytoskeleton suggesting the involvement of WASP in cytoskeletal organization. Close examination of the WASP sequence revealed a putative Cdc42/Rac interacting domain, homologous with those found in PAK65 and ACK. Subsequent investigation has shown WASP to be a true downstream effector of Cdc42.



產(chǎn)品名稱:Rabbit Anti-WASP protein antibody

Rabbit Anti-WASP protein 

別名:Eczema thrombocytopenia; IMD2; SCNX; THC; THC1; Thrombocytopenia 1 (X linked); U42471; Was; WASp; WASP_HUMAN; Wiskott Aldrich syndrome (eczema thrombocytopenia); Wiskott Aldrich syndrome; Wiskott Aldrich syndrome protein; Wiskott-Aldrich syndrome protein.                 

來源:Rabbit

克隆類型:Polyclonal

濃度:1mg/ml

亞型:IgG

反應(yīng):Human,Mouse (predicted: Rat,Rabbit,Cow)

應(yīng)用: WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

       IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

理論分子量:53kDa

免疫原:KLH conjugated synthetic peptide derived from human WASP protein

保存:-20
保質(zhì)期:1

 

 

產(chǎn)品名稱:Anti-WASP protein antibody

Mouse Anti-WASP protein

別名:Eczema thrombocytopenia; IMD2; SCNX; THC; THC1; Thrombocytopenia 1 (X linked); U42471; Was; WASp; WASP_HUMAN; Wiskott Aldrich syndrome (eczema thrombocytopenia); Wiskott Aldrich syndrome; Wiskott Aldrich syndrome protein; Wiskott-Aldrich syndrome protein.                   

來源:Mouse

克隆類型:Monoclonal

濃度:1mg/ml

亞型:IgG

反應(yīng):Human

應(yīng)用:WB=1:1000-1:2000,Elisa=1:1000-1:2000,IHC-P=1:100-500

       IHC-F=1:100-500,ICC/IF=1:100-500,IF=1:100-500

反應(yīng):  Human

理論分子量:53kDa

免疫原:KLH conjugated synthetic peptide derived from human WASP protein

保存:-20
保質(zhì)期:1

The Wiskott-Aldrich syndrome (WAS) is a disorder that results from a monogenic defect that has been mapped to the short arm of the X chromosome. WAS is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative disease. The gene that is mutated in the syndrome encodes a proline-rich protein of unknown function designated WAS protein (WASP). A clue to WASP function came from the observation that T cells from affected males had an irregular cellular morphology and a disarrayed cytoskeleton suggesting the involvement of WASP in cytoskeletal organization. Close examination of the WASP sequence revealed a putative Cdc42/Rac interacting domain, homologous with those found in PAK65 and ACK. Subsequent investigation has shown WASP to be a true downstream effector of Cdc42.


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